Essentials of Clinical Research (Google eBook)

Front Cover
Stephen P. Glasser
Springer Science & Business Media, Jul 20, 2008 - Medical - 376 pages
0 Reviews
This book is designed to provide the student interested in clinical research a foundation upon which to build more advanced study. The book focuses on clinical trials, in contrast to the many excellent textbooks that address epidemiological research. With the recent interest in patient oriented research, this book should provide a knowledge base that is not necessarily covered in other texts. Chapters discussing the FDA s role in clinical research, Data Safety and Monitoring Boards, Postmarketing studies, the use of placebo controls, and a focus on clinical trials illustrates this point. In addition, new types of clinical research are evolving, and as such, this book discusses genetic, pharmacoepidemiologic, and implementation research. Finally, chapters on tips on how to write a grant, the mentoring process, and how to present ones research results are unique to this book.
  

What people are saying - Write a review

We haven't found any reviews in the usual places.

Contents

Clinical Research Definitions Anatomy and Physiology and the Quest for Universal Truth
3
Introduction to Clinical Research and Study Designs
12
Chapter 3 Clinical Trials
29
Alternative Interventional Study Designs
63
Postmarketing Research
72
The United States Federal Drug Administration FDA and Clinical Research
93
The Placebo and Nocebo Effect
111
Recruitment and Retention
141
Implementation Research Beyond the Traditional Randomized Controlled Trial
217
Research Methodology for Studies of Diagnostic Tests
245
Statistical Power and Sample Size Some Fundamentals for Clinician Researchers
261
Association Cause and Correlation
279
Bias Confounding and Effect Modification
295
Its All About Uncertainty
303
Chapter 19 Grant Writing
317
The Media and Clinical Research
329

Data Safety and Monitoring Boards DSMBs
150
Chapter 10 MetaAnalysis
159
Research Methods for Genetic Studies
179
Research Methods for Pharmacoepidemiology Studies
201
Mentoring and Advising
334
Presentation Skills How to Present Research Results
341
Index
351
Copyright

Common terms and phrases

Popular passages

Page 5 - The consequence was, that the most sudden and visible good effects were perceived from the use of the oranges and lemons ; one of those who had taken them, being at the end of six days fit for duty.
Page 5 - On the 20th of May, 1747, I took twelve patients in the scurvy, on board the Salisbury at sea. Their cases were as similar as I could have them. They all in general had putrid gums, the spots and lassitude, with weakness of their knees.
Page 5 - These they eat with greediness, at different times, upon an empty stomach. They continued but six days under this course, having consumed the quantity that could be spared. The two remaining patients, took the bigness of a nutmeg three times a day...

Bibliographic information