Asthma: Etiology, Pathogenesis and Treatment
Asthma is characterised by intermittent airway obstruction, bronchial smooth muscle cell hyper-reactivity to broncho-constrictors, and chronic bronchial inflammation. The aetiology of asthma is heterogeneous with a number of established risk factors. The prevalence of asthma has been increasing in all age and racial groups during the past two decades. The variation in prevalence rates for racial and ethnic groups probably results from differences in genetic, environmental, social, and cultural influences. Factors affecting increased asthma prevalence include obesity and exposure to environmental irritants. The population has become increasingly sedentary, spending more time indoors where the exposure to allergens, such as mould, dust mites, and cockroach dust, is more prevalent. In addition, the increased prevalence of allergic rhinitis and atopy related to exposure to allergens at an early age is associated with the prevalence of asthma. This book provides new research on this field from around the globe.
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Can Fish Oil Supplementation Protect against Asthma?
Validity and Reliability of the Standardized Asthma
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157insMTTTVP activity limitations adults air pollution airway allele allergen Allergy Allergy Clin Immunol AQLQ arachidonic acid aspirin aspirin-induced asthma asthma words asthmatic group asthmatic patients atopic phenotype atopy attentional bias boys bronchial asthma bronchoconstriction children with asthma chronic bronchitis clinical control participants Crit cyclooxygenase Cys-LTs cytokines dietary disease drugs effect eicosanoids emission emotional functioning environmental stimuli enzyme eosinophils exercise-induced exposure to environmental factors fatty acids fish oil fish oil supplementation girls HAV infection Health hygiene hypothesis increased induced asthma inflammation inflammatory inhaled inhibition Journal Juniper leukotriene C4 LTC4 LTC4 synthase LTE4 mediated medication mild mothers n-3 PUFA nasal polyps negative affectivity NF-kB Nizankowska normal NSAIDs parents patients with AIA patients with asthma PGD2 PGE2 prevalence of asthma prostaglandin prostanoids questionnaire reaction receptor Research Respir respiratory response RydstrOm severe asthma significant differences significantly smoking strategies symptoms Szczeklik total AQLQ(S uncertainty validity Yokkaichi Yokkaichi Asthma