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abdominal abnormalities abortion activity acute adoles adolescent adrenal adult amenorrhea androgen anemia anorexia nervosa associated birth bleeding Cancer carcinoma cause cell tumors cervical cervix child chronic Clin Endocrinol Metab clinical congenital cortisol cysts decreased DES-exposed diagnosis differential disease disorders drug dysgerminoma dysmenorrhea effects endo endocrine endometrial endometriosis estradiol estrogen etal evaluation factors female fetal function genital genitalia germ cell germ cell tumors girls GnRH gonadal gonadotropin growth gynecologic hormone increased infants infection iron deficiency lesions levels male malignant maturation menarche menstrual metabolic normal nutritional Obstet Gynecol occur onset oral contraceptives ovarian parents patients Pediatr pelvic inflammatory disease pill pituitary plasma polycystic ovary precocious puberty pregnancy prepubertal problems progesterone progestin prolactin puberty reported response result risk salpingitis secretion serum sex steroid sexual stage steroids studies surgical symptoms syndrome teenagers teratoma testicular testosterone therapy tion tissue treatment usually uterine vaginal weight women