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accumulation acetylcholinesterase acrylamide Acta actin activity adrenergic amino acids amount ATPase axonal transport axoplasmic transport Biochem block Brain Res Ca2+ calcium calmodulin Cell Biol cell body cholinergic colchicine components crush cytoplasm cytoskeletal decrease desheathed diabetes distal dorsal root ganglion effect enzymes experimental fast axonal transport fast-transported proteins fraction fucose function glycoproteins goldfish optic Grafstein Hammerschlag increase inhibition injection intracellular labeled proteins Lasek ligation mammalian nerve mechanism metabolism microtubules mm/day molecular weight molecules motor movement muscle myelinated nerve fibers neurites Neurobiol Neurochem neurofilaments neurons neuropathy Neurosci observed Ochs optic nerve organelles peptide peripheral nerve Physiol polypeptides proteoglycans proximal radioactivity rat sciatic nerve regenerating retrograde retrograde axonal transport retrograde transport role sciatic nerve sensory slow-transport soluble squid squid giant axon streptozotocin studies subcellular substances sulfate synthesis tissue transport of proteins transported glycoproteins transported material transported proteins tRNA trophic tubulin velocity vitro