An Introduction to Biomaterials
Jeffrey O. Hollinger
CRC Press, Dec 21, 2005 - Medical - 576 pages
The complexity of biological systems and the need to design and develop biomedical therapies poses major challenges to professionals in the biomedical disciplines.
An Introduction to Biomaterials emphasizes applications of biomaterials for patient care. Containing chapters prepared by leading authorities on key biomaterial types, this book underscores the process of biomaterial design, development directed toward clinical application, and testing that leads to therapies for clinical targets.
The authors provide a lucid perspective on the standards available and the logic behind the standards in which biomaterials address clinical needs. This volume includes chapters on consensus standards and regulatory approaches to testing paradigms, followed by an analysis of specific classes of biomaterials. The book closes with sections on clinical topics that integrate materials sciences and patient applications.
Protein Adsorption at the BiomaterialTissue Interface
In Vitro Testing of Biomaterials
Considerations for the In Vivo Testing of Biomaterials
Fibrin and Its Applications
Proteins and Amino AcidDerived Polymers
Biomaterials for Drug and Gene Delivery
Orthopedic Prostheses and Joint Implants
Tissue Engineering of Bone
In identifying fundamental biological requirements of a biomaterial numerous
As discussed in accompanying chapters all materials implanted into the human body
Polymers Derived from LTyrosine
Hyaluronan as a Biomaterial
Tissue Engineering Nervous System
Cardiovascular Tissue Engineering
Tissue Engineering Skin
Tissue Engineering of Ligaments
Tissue Engineering of Articular Cartilage
adsorption alginate Allcock alloys amino acids applications assays ASTM biocompatibility biodegradable Biol biological biomaterials Biomed biomedical calcium carbonate cellular ceramics chain chemical chitosan clinical collagen components composition concentration copolymers cross-linking culture defects degradation delivery systems dental implants differentiation diffusion drug delivery effects elastin endothelial ester evaluation extracellular fibers fibrin clot fibrin sealant fibrinogen fibroblasts Figure fracture function gene delivery glycolide graft groups growth factor healing human hyaluronan integrin interactions interface keratinocytes Kohn materials matrix mechanical properties medical devices membrane mesenchymal stem cells metal Mikos modulus molecular weight molecules monomer orthopedic osseointegration osteoblasts patients peptide plasma poly(DTE polyglycolide polymer polymerization polyphosphazenes polyurethane potential proliferation prostheses protein adsorption receptors regeneration release response scaffolds segment soluble spinal stem cells stress structure studies surface synthesis synthetic temperature testing therapy tissue engineering toxicity UHMWPE vitro vivo