Acute effects of inhalation exposure to uranium hexafluoride and patterns of deposition: UF6/UO2F2 studies in experimental animals, report period: June 1978-July 1979
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24 hours absorbed dose administered dose administration aerosol ANIMAL SPECIES biochemical burden of uranium carcass CM CM control on day convoluted tubules Cumulative Uranium Excretion DAYS AFTER TREATMENT days post-instillation days postexposure Distribution and Excretion Dog Studies dosage elimination of uranium Excretion In Inhalation excretion rate feces fibrin g INITIAL gastrointestinal tract glomerular filtration rate glucosuria histopathologic ICRP Inhalation Exp Inhalation Experiment Inhalation Exposure INHALATION NOSE inhalation studies initial body burden intake intratracheal intratracheal instillation intravenous kidneys MALES BODY WEIGHT mg kg mg kg-1 mg U kg MMAD necrosis nephron nephrotoxic normal on day Nuclear Regulatory Commission percent of control Plasma Urea Nitrogen proteinuria RAT STRAIN Retention functions Rodent sacrificed STRAIN AND SEX Table TEST COMPOUND thoracic tissue toxicity uranium content Uranium Hexafluoride uranyl fluoride uranyl nitrate urinary elimination urinary excretion Urinary Glucose urinary protein urine whole body retention