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acute affective disorder affective illness agents agoraphobia alprazolam anorexia nervosa anorexic patients antipsychotic anxiety disorders anxiolytic Arch Gen Psychiatry associated behavior beneﬁt benzodiazepines binge eating bipolar blockade blood levels breakthrough depressions bulimia bulimic bulimic patients bulimic subjects buspirone carbamazepine chlordiazepoxide chronic Clin Psychiatry clinician compliance concem decrease depressive symptoms diagnosis diazepam difﬁcult Docherty dopamine dosage doses double-blind drug treatment DSM-III eating disorders effects of neuroleptics efﬁcacy episodes evaluation extrapyramidal side effects ﬁndings ﬁrst frequently Gwirtsman half-life haloperidol hepatic imipramine increased inﬂuence interactions Iohnson lithium lorazepam major depression MAOIs medication ment metabolism mg/day noncompliance onset outpatient Oxidative panic disorder percent pharmacological phobias physician placebo potential problem propranolol psychopharmacology Psychopharmacology Consultation psychosis psychosocial psychotherapy psychotic recent receptor relapse relationship reported response schizo schizoaffective illness schizophrenia schizophrenic patients sedation speciﬁc studies suggest syndrome tardive dyskinesia therapeutic therapy tients tion treat treatment program trial tricyclic weight gain withdrawal