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Inhibition of Prostaglandin Biosynthesis
Catecholamine Induced Increase in Prostaglandin E Biosynthesis in Homogenates
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acid secretion action of prostaglandins activity adenyl cyclase administered aldosterone arachidonic acid arteries aspirin assay ATPase basal Biochem Biol Biophys biosynthesis blood flow blood pressure bradykinin Brit cells cerebral Chem chromatography compounds concentration cortex cyclic AMP decrease derivative dose drugs Effect of prostaglandin endogenous enzyme ester ethanol experiments extracted formation glandins guinea pig histamine hormone human hypertension increase incubation indomethacin induced infusion inhibitor injection intravenous isolated isomerase kidney levels lipid lung mass mass spectrometry medulla metabolism metabolite method methyl methyl ester mg/kg Mg/ml mice nerve stimulation ng/ml norepinephrine normal patients perfusion PG synthetase PGA2 PGE2 PGEi PGEj PGF2a Pharmac Pharmacol phosphate plasma polyphloretin phosphate produced prosta prostaglandin antagonists prostaglandin E2 rabbit Ramwell release renal response Samuelsson Scand serum shown in Fig smooth muscle sodium specific studies substrate tion tissue urine Vane vascular venous vitro vivo