Neuroinflammation: Mechanisms and Management

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Paul L. Wood
Humana Press, Dec 18, 2002 - Medical - 419 pages
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Neuroinflammation is an important area of study in that a large number of neurodegenerative disorders demonstrate sustained inflammation within the neuraxis. In the second edition of Neuroinflammation, Mechanisms and Management, chapters are updated to review newly discovered mediators of neuroinflammation, as well as other CNS disorders. This edition puts into perspective the many various theories of neurodegeneration and the relevance of neuroinflammation. As with the first edition, a balanced evaluation of both basic and clinical data is presented along with several new chapters focussed on animal models. The conceptual framework provided by current concepts of neuroinflammation in neurological disorders has provided testable approaches for clinical studies in patient populations for which there is no current treatment. This text integrates preclinical research, human autopsy data, and current clinical concepts to provide in-depth overviews of the potential role of neuroinflammation in a number of devastating neurological disorders. Neuroinflammation Mechanisms and Management aims to stimulate interactions between basic scientists (molecular biologists, biochemists, immunologists, anatomists and pharmacologists) and neurologists dealing with the complex clinical issues associated with these diverse clinical conditions. The book provides well-referenced and integrated reviews along with tabular presentations of useful reference data for both clinicians and scientists.

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