An Introduction to Vascular Biology: From Basic Science to Clinical Practice

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Cambridge University Press, Jul 25, 2002 - Medical - 458 pages
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Vascular biology is an exciting and rapidly advancing area of medical research, with many new and emerging pathophysiological links to an increasing number of diseases. This updated and expanded new edition takes full account of these developments and conveys the basic science underlying a wide range of clinical conditions including atherosclerosis, hypertension, diabetes, and pregnancy. As with the first edition, the publication provides an introductory account of vascular biology before leading on to explain mechanisms involved in disease processes.
  

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Contents

Vascular tone
3
Vascular compliance
33
Flowmediated responses in the circulation
49
Neurohumoral regulation of vascular tone
70
Angiogenesis basic concepts and the application of gene therapy
93
The regulation of vascular smooth muscle cell apoptosis
114
Wound healing laboratory investigation and modulating agents
129
Pathophysiology mechanisms and imaging
167
Clinical practice
283
Vascular biology of hypertension
285
Atherosclerosis
302
Abdominal aortic aneurysm
318
The vasculature in diabetes
327
The vasculitides
343
Pulmonary hypertension
361
Role of endothelial cells in transplant rejection
381

Genes for hypertension
169
The endothelium in health and disease
186
Nitric oxide
216
Magnetic resonance imaging in vascular biology
259
Vascular function in normal pregnancy and preeclampsia
398
Index
427
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About the author (2002)

Matthew W. Gillman is Director of the Obesity Prevention Program and Professor in the Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute and is Professor in the Department of Nutrition, Harvard School of Public Health, Boston, MA, USA.

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