Bile acids and cholestasis: (XV International Bile Acid Meeting) : proceedings of the Falk Symposium 108 (Part 1 of the Gastrointestinal Week Titisee 1998) held in Titisee, Germany, October 12-13, 1998

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Kluwer Academic Publishers, 1999 - Medical - 291 pages
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Since the last International Bile Acid Meeting in Freiburg in 1996, considerable progress has been made in several areas of bile acid research. The different pathways of bile acid synthesis and their regulation have been further characterized. The molecular mechanisms for biliary secretion of bile acids have been elucidated and genetic defects of bile acid transport have been defined. Injurious as well as protective effects of different bile acids on the liver have been further studied. Finally, the beneficial effects of ursodeoxycholic acid in cholestatic liver diseases have been substantiated and the potential mechanisms of action have been explored. This book, the proceedings of the Falk Symposium No. 108 (XV International Bile Acid Meeting), held in Titisee, Germany, October 12-13, 1998, is dedicated to both basic and clinical aspects of bile acid research with a focus on bile acids and cholestasis.

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Contents

The regulation of different bile acid biosynthetic pathways
31
Transcriptional regulation of the cholesterol
51
Substrate specificity of NaVbile acid cotransporters
77
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