Heme Oxygenase: Clinical Applications and Functions

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CRC Press, Jun 16, 1992 - Medical - 288 pages
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his book provides a comprehensive summary of data from basic research on characterization, regulation, and function of heme oxygenase in mammalian systems. The book also includes a major section that covers the currently used clinical methods to suppress neonatal jaundice with emphasis on the newly developed use of synthetic metalloporophyrins. This book will be welcomed by researchers and students in pharmacology, biochemistry, pharmacy, neonatology, hematology, internal medicine, and endocrinology.
  

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Contents

Chapter
1
Porphobilinogen Deaminase and Uroporphyrinogen III Synthetase
24
Chapter 2
43
Chapter 6
46
References
58
Enzymatic Degradation of Heme by Heme Oxygenase
67
Role of NADPHCytochrome P450 Reductase in Regulation
77
References
96
Chapter 5
145
Mechanisms of Heme Oxygenase Regulation
155
References
180
Neonatal Jaundice
203
Toxicity of Bilirubin to the Newborn
211
Possible Physiological Importance of Bilirubin
219
References
253
Index
267

Chapter 4
109
References
138

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Popular passages

Page 265 - Coupling of dopamine oxidation (monoamine oxidase activity) to glutathione oxidation via the generation of hydrogen peroxide in rat brain homogenates, J. Neurochem.
Page 263 - Schmid R: Catabolism of heme in vivo: Comparison of the simultaneous production of bilirubin and carbon monoxide. J Clin Invest 49:914, 1970 19.

References to this book

Heme-Fe Proteins, Volume 51

Limited preview - 2000
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