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abnormal acidosis activity acute allograft Amer amino acids antibody antigens bacteria bacteriuria biochemical bladder Brit calcification calcium oxalate calcium phosphate cause cells chronic renal failure clearance clin clinical concentration creatinine crystalluria crystals cystine cystinuria diagnosis dietary distal diuresis dose drug effect enzyme excretion factors fluid glomerular filtration rate graft Hodgkinson hormone hyper hypercalcaemia hypercalciuria Hyperoxaluria hyperparathyroidism hypertension Idiopathic increased intravenous kidney Lancet lesions levels magnesium matrix measured mechanism metabolic necrosis nephrocalcinosis nephron normal occur papilla parathyroid patients penicillamine perfusion plasma calcium present pressure produced protein proximal tubule pyelonephritis reabsorption rejection renal artery stenosis renal blood flow renal calculi renal disease renal function Renal Stone renal tubular renin segment artery serum sodium solubility stone formation stone-formers studies substance technique tissue transplantation treatment tumour urea uric acid urinary calcium Urinary Calculi urinary infection urinary tract infection urine Urol Urolithiasis vascular venous vitamin xanthine xanthinuria