ART and the Human Blastocyst
David K. Gardner, Michelle Lane
Springer Science & Business Media, Jan 1, 2001 - Health & Fitness - 254 pages
The continued debate regarding the stage at which the human embryo conceived in the laboratory should be placed in the mother, combined with recent developments in culture media formulations, have brought the role of the human blastocyst in ART back into the spotlight. ART and the Human Blastocyst presents the proceedings of the International Symposium on ART and the Human Blastocyst held from March 30- April 2, 2000 in Dana Point, California. This book brings to the forefront the main issues raised with the transfer of embryos at the blastocyst stage, including the reduction of high order multiple gestations and the role of the blastocyst culture and transfer in facilitating successful single embryo transfer. Sections include gamete quality and pregnancy outcome, physiology of the embryo, blastocyst development in culture, blastocyst transfer and fate, and implantation. More than 40 illustrations and 25 tables complement the text.
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The Impact of HighOrder Multiple Pregnancies
Patient Stimulation and Effect on Outcomes
New Developments in Imaging and Hormonal Stimulation of the Ovaries
Paternal Effects on Fertilization Embryo Development and Pregnancy Outcome
The Cell Biology of Preimplantation Development
Metabolism of the Early Embryo Energy Production and Utilization
Cell Junctions and Cell Interactions in Animal and Human Blastocyst Development
Which Patients Should Have Blastocyst Transfer?
Embryo Transfer and Luteal Phase Support
Cryopreservation of Blastocysts
EmbryoMaternal Dialogue in the Apposition and Adhesion Phases of Human Implantation
Biomarkers and the Assessment of Uterine Receptivity
Endometrial Pinopodes Relevance for Human Blastocyst Implantation
The Future Toward Single Embryo Transfer
The Niche of the Blastocyst in Human ART
activity adhesion agonist amino acids antiporter apoptosis assisted reproductive technologies Biol Reprod blasto blastocyst blastocyst culture blastocyst development blastocyst formation blastocyst stage blastocyst transfer blastomeres bovine bryos calcium cleavage stage cleavage-stage embryos clinical cryopreservation culture media culture system cycles effect embryo culture embryo development embryo transfer endometrial endometrium expression Fertil Steril follicles Gardner DK gene gestations GnRH gonadotropin growth factor hamster high-order multiple hormone Hum Reprod human blastocysts human embryos hyaluronan ICSI IGF-I implantation rates increase infertility integrin intracellular pH Leese HJ Lessey BA levels mammalian medium membrane metabolism Mol Reprod Dev morula mouse embryos MUC1 multiple births multiple pregnancy number of embryos oocyte ouabain ovarian oviduct ovulation patients phase pinopodes potential pregnancy rates preimplantation development preimplantation embryo protein pyruvate receptors regulation Reprod Fertil role serum sperm stimulation tight junction tion triplet trophectoderm twin uterine receptivity viability vitro fertilization vivo zygote