ART and the Human Blastocyst

Front Cover
David K. Gardner, Michelle Lane
Springer Science & Business Media, Jan 1, 2001 - Health & Fitness - 254 pages
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The continued debate regarding the stage at which the human embryo conceived in the laboratory should be placed in the mother, combined with recent developments in culture media formulations, have brought the role of the human blastocyst in ART back into the spotlight. ART and the Human Blastocyst presents the proceedings of the International Symposium on ART and the Human Blastocyst held from March 30- April 2, 2000 in Dana Point, California. This book brings to the forefront the main issues raised with the transfer of embryos at the blastocyst stage, including the reduction of high order multiple gestations and the role of the blastocyst culture and transfer in facilitating successful single embryo transfer. Sections include gamete quality and pregnancy outcome, physiology of the embryo, blastocyst development in culture, blastocyst transfer and fate, and implantation. More than 40 illustrations and 25 tables complement the text.
  

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Contents

The Impact of HighOrder Multiple Pregnancies
3
Patient Stimulation and Effect on Outcomes
21
New Developments in Imaging and Hormonal Stimulation of the Ovaries
29
Paternal Effects on Fertilization Embryo Development and Pregnancy Outcome
38
The Cell Biology of Preimplantation Development
51
Metabolism of the Early Embryo Energy Production and Utilization
61
Blastomere Homeostasis
69
Cell Junctions and Cell Interactions in Animal and Human Blastocyst Development
91
Which Patients Should Have Blastocyst Transfer?
167
Embryo Transfer and Luteal Phase Support
184
Cryopreservation of Blastocysts
188
EmbryoMaternal Dialogue in the Apposition and Adhesion Phases of Human Implantation
199
Biomarkers and the Assessment of Uterine Receptivity
210
Endometrial Pinopodes Relevance for Human Blastocyst Implantation
227
The Future Toward Single Embryo Transfer
236
The Niche of the Blastocyst in Human ART
241

Blastocyst Development in Culture The Role of Macromolecules
105
Culture Systems and Blastocyst Development
118
Apoptosis in the Human Blastocyst Role of Survival Factors
144
Predictors of Viability of the Human Blastocyst
155

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About the author (2001)

David K. Gardner is Head of the Department of Zoology, University of Melbourne, Australia.

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