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activity age cohort age groups age-related ageing population Alzheimer Alzheimer's disease amyloid aortic stenosis Arie assessment blood pressure bone density bone loss brain breast cancer calcium cardiac cardiovascular disease causes cells cerebral cortex changes chronic Clin clinical cognitive colorectal cancer coronary cortex costs decrease dementia developing countries diagnosis drugs effect elderly patients elderly population expectancy Foundation Symposium 134 Fries function gene Geriatr Gerontology health services hip fracture hospital hypertension immune impairment incidence increase individuals infection Institute intervention Katzman Kirkwood living long-term longitudinal study major Mellstrom menopause mental morbidity mortality myocardial infarction neurofibrillary tangles neurons normal nursing home nursing-home old age older patients organism osteoporosis Phair present prevalence problems programmes response risk factors scenarios senescence social socioeconomic specific stroke suggest survival Svanborg systolic T.F. Williams therapy tion treatment ventricular Wenger women younger patients