Drug Design of Zinc-Enzyme Inhibitors: Functional, Structural, and Disease Applications (Google eBook)
Claudiu T. Supuran, Jean-Yves Winum
John Wiley & Sons, Oct 22, 2009 - Medical - 912 pages
Brings together functional and structural informationrelevant to the design of drugs targeting zinc enzymes
The second most abundant transition element in living organisms, zinc spans all areas of metabolism, with zinc-containing proteins offering both established and potential drug targets. Drug Design of Zinc-Enzyme Inhibitors brings together functional and structural information relevant to these zinc-containing targets. With up-to-date overviews of the latest developments field, this unique and comprehensive text enables readers to understand zinc enzymes and evaluate them in a drug design context.
With contributions from the leaders of today's research, Drug Design of Zinc-Enzyme Inhibitors covers such key topics as:
An essential resource for the discovery and development of new drug molecules, Drug Design of Zinc-Enzyme Inhibitors gives researchers, professionals, students, and academics the foundation to understand and work with zinc enzyme inhibitors and activators.
What people are saying - Write a review
Saying the truth, this book could be better. Unfortunately, Google gave me a limited time to look through it and I have to rely on my first impression. I think, the book is adequate to what we used to know about MMPs and their inhibitors 10-15 years ago. However, you have to find something else if collection of antique artifacts is not your primary goal in Science. There is some progress made lately and this book simply does not reflect it. I feel deceived and disappointed. Perhaps, I will find something better.
PART III DRUG DESIGN OF MATRIX METALLOPROTEINASE INHIBITORS
PART IV DRUG DESIGN OF BACTERIAL ZINC PROTEASE INHIBITORS