Bioartificial Organs Two
New YorkAcademy of Sciences, 1999 - Science - 415 pages
This book deals with bioartifical organ replacements, including the bioartifical pancreas (diabetes) and the bioartifical liver and skin. It also discusses new developments in the craniofacial and cartilage areas; tissue sourcing (xeno and allografs), and the suitability of xenotransplantation for immunoisolation devices. Advances in genetically modified cells are also highlighted, as are the molecular aspects of rejection prevention, new biomaterials, and processing.
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acid activation adhesion alginate allogeneic allograft animals antibodies antigen Artif artificial beads bioartificial liver bioreactor Biotechnol blood BLSS bone capsules cartilage cell line cellular chitosan chondrocytes collagen complement cryopreserved CTLA4-Ig culture cytokines device diabetic diffusion donor encapsulated cells encapsulated islet enzyme extracorporeal factor FIGURE function gene therapy genetically engineered glucose graft growth hepatic failure hepatocytes hollow fiber hydrogel immobilization immune immunoisolation immunosuppression implanted incubation insulin insulin secretion islet cells islet transplantation islet xenografts islets of Langerhans isolation layer liver failure liver support medium membrane metabolic microbead microcapsules molar mass molecular molecules NOD mice oxygen P-cell pancreatic pancreatic islet pathway patients peptide perfusion plasma polymer porcine islets potential Proc production protein PSSa Rajotte rat islets reaction response rhBMP-2 serum solution sponges studies surface survival tion tissue engineering transgenic treatment vascular viability vitro vivo xenogeneic xenografts xenotransplantation