Hematopoietic Stem Cell Development (Google eBook)

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Springer Science & Business Media, May 27, 2010 - Medical - 190 pages
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Hematopoietic Stem Cells brings together articles covering the biology of hematopoietic stem cells during embryonic development, reporting particular aspects of fly, fish, avian and mammalian models. Thus, this book allows a comparative overview of hematopoietic stem cell generation in the different classes, emphasizing the conserved trends in development. This book culminates with state-of –the art knowledge on hematopoietic development in human species and discussions of the most recent breakthroughs with relevance to both researchers and clinicians.
  

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Contents

CHAPTER 1 Ventral and Dorsal Contributions to Hematopoiesis in Xenopus
1
CHAPTER 2 Genetic Dissection of Hematopoiesis Using the Zehrafish
14
CHAPTER 3 Extra and Intraembryonic HSC Commitment in the Avian Model
32
CHAPTER 4 Avian Lymphopoiesis and Transcriptional Control of Hematopoietic Stem Cell Differentiation
46
CHAPTER 5 Yolk Sac Development in Mice
62
CHAPTER 6 LongTerm Reconstituting Hematopoietic Stem Cell Capacity in the Embryo
72
The Cradle of Definitive Hematopoiesis?
80
CHAPTER 8 Endothelial and Hematopoietic Cells in the Intraembryonic Compartment
92
CHAPTER 9 Origin and Fate of Hematopoietic Precursors in the Early Mouse Embryo
108
A Parallel with Vertebrates
124
Expression Analysis
142
CHAPTER 12 Gene and Cell Therapy Involving Hematopoietic Stem Cell
154
Index
175
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