Systematics and Evolution, Part 2

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David J. McLaughlin, E. G. McLaughlin, Paul A. Lemke
Springer Science & Business Media, Sep 22, 2000 - Science - 259 pages
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Mycology, the study of fungi, originated as a subdiscipline of botany and was a des criptive discipline, largely neglected as an experimental science until the early years of this century. A seminal paper by Blakeslee in 1904 provided evidence for self incompatibility, termed "heterothallism", and stimulated interest in studies related to the control of sexual reproduction in fungi by mating-type specificities. Soon to follow was the demonstration that sexually reproducing fungi exhibit Mendelian inheritance and that it was possible to conduct formal genetic analysis with fungi. The names Burgetf, Kniep and Lindegren are all associated with this early period of fungal genet ics research. These studies and the discovery of penicillin by Fleming, who shared a Nobel Prize in 1945, provided further impetus for experimental research with fungi. Thus began a period of interest in mutation induction and analysis of mutants for biochemical traits. Such fundamental research, conducted largely with Neurospora crassa, led to the one gene: one enzyme hypothesis and to a second Nobel Prize for fungal research awarded to Beadle and Tatum in 1958. Fundamental research in biochemical genetics was extended to other fungi, especially to Saccharomyces cerevisiae, and by the mid-1960s fungal systems were much favored for studies in eukaryotic molecular biology and were soon able to compete with bacterial systems in the molecular arena.
  

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Contents

II
3
III
37
IV
57
V
85
VI
121
VII
169
VIII
171
IX
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X
203
XI
217
XII
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XIII
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XIV
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XV
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Copyright

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About the author (2000)

David J. McLaughlin is a published author who has written extensively on the California Missions. His most recent book, Soldiers, Scoundrels, Poets & Priests tells the stories of the men and women behind the missions of California. He is a member of the California Mission Studies Association.