The Cutaneous Lymphoid Proliferations: A Comprehensive Textbook of Lymphocytic Infiltrates of the Skin

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Wiley, Mar 16, 2007 - Medical - 499 pages
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A complete reference to the latest understanding of lymphocytic infiltrates

The Cutaneous Lymphoid Proliferations provides a complete, authoritative treatment of the clinical features, phenotypes, pathogenesis, histopathology, diagnosis, and treatment of lymphocytic infiltrates of the skin. Incorporating the latest findings from the fields of light microscopy, immunohistochemistry, and flow cytometry, the book brings readers up to date on the most current thinking in the field. Those readers familiar with the authors' critically acclaimed The Melanocytic Proliferations will find a similar structure and the same attention to detail and quality in this latest reference.

The book starts off with a clinical atlas and introduction to the ontogeny and biology of the lymphoid system. Next, the authors explore novel molecular approaches to the diagnosis of cutaneous lymphoid proliferations and benign lymphocytic infiltrates. The remaining chapters concentrate on major inflammatory skin diseases and lymphoproliferative disorders, including chronic lymphocytic leukemia, lupus, adult T cell leukemia, and primary cutaneous Hodgkin's disease.

As a reference to lymphocytic infiltrates, this book is unsurpassed. Novice and experienced practitioners alike will gain important insights into the field, including:

  • The role of the immune system in the pathogenesis of cutaneous disease
  • Relationships between therapeutic drugs and cutaneous eruptions
  • Important drug reactions

Hundreds of full-color, high-quality clinical and histologic photographs help readers visualize the various infiltrates and their treatments. Having this reference on hand is essential for all dermatologists, dermatopathologists, oncologists, and general pathologists who need a synthesis of the current thinking in the field.

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About the author (2007)

CYNTHIA M. MAGRO, M.D., is Professor of Pathology and Director of Dermatopathology at Weill Medical College of Cornell University in New York City. She has published extensively in the areas of inflammatory skin disease, including collagen vascular disease, vasculitis, cutaneous manifestations of systemic disease, and unique drug hypersensitivity reactions. A significant focus of her work has been lymphocytic infiltrates, including unique forms of drug reactions such as the interstitial granulomatous drug reaction and drug-associated reversible T cell dyscrasia; prelymphomatous cutaneous lymphoid dyscrasias including atypical lymphocytic lobular panniculitis pityriasis lichenoides chronica and pigmented purpuric dermatosis; and malignant T and B cell lymphomas. She has extended her work in immune mechanisms of skin disease and applied it to areas of lung transplantation and pulmonary fibrosis.

A. NEIL CROWSON, M.D., is Clinical Professor of Dermatology, Pathology, and Surgery, and Director of Dermatopathology at the University of Oklahoma and Regional Medical Laboratory in Tulsa, Oklahoma. His current research interests focus on mechanisms of neoplastic and inflammatory skin disease.

MARTIN C. MIHM, Jr., M.D., is Clinical Professor of Pathology and Dermatology at Harvard Medical School, Massachusetts General Hospital. He is internationally recognized for his expertise in the pathology, diagnosis, and management of pigmented lesions, lymphoid disorders, and vascular tumors. He has worked extensively to understand the host response to melanoma and other tumors. He has served as codirector of the WHO Melanoma Program in addition to his many obligations in translational and clinical research in cutaneous inflammation, tumor vaccination, and pathogenesis of vascular lesions in children.

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