Cancer Chemotherapy Reports: Part 2, Volumes 2-3U.S. Department of Health, Education, and Welfare, Public Health Service, National Institutes of Health, 1971 - Antineoplastic agents |
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1/10 expt inoc 9H-Purine 9H-Purine-6-thiol activity Adenine adenosine advanced leukemia L1210 alkylating agents amino analogs antibiotics antileukemic antitumor assay Avg tumor diam Avg wt change BCNU C₁ Cancer Chemother Rep Cancer Res Carbamic acid CAS reg cells/mouse CH₂OSO2CH3 Chemotherapy Compound name Cyclophosphamide daily days after tumor deaths Avg tumor diet dimethanesulfonate dimethanesulfonate ester dose tested drug entry ester Ethanol ethyl ester experimental inoc expt inoc Controls fonate gav 1 9 Glutamic acid guanidine H₂O hydrochloride inhibition KB cell leukemia leukemic Median survival ment Methanesulfonic acid methotrexate methyl mg/kg/day mitomycin molecular formula monohydrate monohydrochloride Mortality distribution days N₂O NSC SK Number optimal dose porfiromycin purine Pyrimidine Results at end sc treatment screening sulfonate survivors Day thiosemicarbazone toxicity treat treated/control Tumor index treatment schedule tumor tumor diam cm tumor-active TWI OD TWI Untreated without tumor Urea Vehicle control vitro vivo week Avg wt