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Melanocytes and Their Tumors
Malignant Tumors Melanomas and Related Lesions
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acquired nevi acral amelanotic and/or areas associated atypia atypical benign biopsy Cancer cell nevus cell type characteristic Clinical Features collagen compound nevus criteria cutaneous cytoplasm dendritic dermal component dermal nevus Dermatol desmoplastic melanoma Differential Diagnosis dysplastic nevi eosinophilic epidermis epithelioid cells excision fascicles Figure giant congenital nevi growth phase melanoma halo nevus higher magnification histologic infiltrate intraepidermal invasion junctional keratinocytes lentiginous lentigo maligna melanoma lesional cells lymphocytes malignant melanoma maturation melanin melanin pigment melano melanocytic nevi melanoma cells metastases Microscopic Features mitoses mitotic rate necrosis neoplasm nests nevus cells nodular melanoma noma nucleoli pagetoid spread papillary dermis Pathol Pathology patients pattern percent pigment pigmented spindle cell plaque present primary prognostic radial growth phase regression rete ridges reticular dermis risk scanning magnification seen sions skin spindle and epithelioid spindle cell Spitz nevi stains superficial spreading melanoma thickness tion tumor tumor cells tumorigenic ulceration usually variable variant vertical growth phase