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acid activity adhesion airway alginate alveolar macrophages analysis antibody antigen apoptosis assay asthma BAL fluid binding Biol biopsies blood bronchial bronchoalveolar buffer cancer cDNA cell line Cell Mol cellular CFTR chemotactic Clara cell Clin clone concentration culture cytokines detected differentiation effect eosinophils epithelial cells epithelium explants exposure fibroblasts fibrosis fibrotic Figure gene expression growth factor Hox genes hybridization hyperoxia Immunol immunoreactivity increased incubated induced inflammation inflammatory inhibition inhibitor instillation interleukin isolated lavage leukocytes levels lung tissue lymphocytes macrophages mast cells membrane mice Molecular molecule monocytes monolayers mouse mRNA murine neutrophil ng/ml normal Northern blot Panel patients Physiol plasmin platelets probe production proliferation protein pulmonary rabbit rats receptor Respir Respiratory response role saline sequence serum shown SP-A SP-C staining stimulated supernatants surface synthase tion TNF-a TNFa transcription TSMC tumor necrosis type II cells vascular vitro vivo