Post-traumatic Arthrosis: Cartilage Markers in Joint Fluid for the Identification of Patients at RiskDepartment of Orthopaedics, University Hospital, Lund University, 1994 - Osteoarthritis |
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activity acute aggrecan fragments analysis Arthritis Rheum arthroscopy arthrosis aspirated average Bone cartilage matrix changes chronic phase clinical COMP compared concentrations of aggrecan correlation cruciate ligament cruciate ligament injury Dahlberg detection determine developing disease early effect evaluated examination Figure findings fluid samples four fragments in joint Further group of patients Heinegård higher human hyaluronan included increased individual influence injection injured and uninjured intra-articular joint cartilage joint disease joint fluid knee injury lateral lesions less levels Lohmander L S lower Lund marker mass mean median Medical meniscus molecular normal obtained Orthop osteoarthritis patients PG fragments placebo present study proteoglycan fragments pseudogout radiographic range ratio reference group relation release represent saline Saxne serum showed significant stages stromelysin-1 stromelysin-1 and TIMP-1 suggested symptoms synovial fluid Table tear TIMP tissue trauma treatment uninjured knee University values volume weeks µg/ml