Pathophysiology of Heart FailureNaranjan S. Dhalla, Pawan K. Singal, Nobuakira Takeda, Robert E. Beamish Pathophysiology of Heart Failure brings together leading basic scientists and clinicians, presenting new approaches to this complex problem, involving cardiomyopathic processes and ischemia perfusion injury. The result is a synthesis of state-of-the-art information on molecular biology, cellular physiology and structure-function relationships in the cardiovascular system. The role which excess intracellular calcium plays in the genesis of cardiac dysfunction is described as a fundamental mechanism underlying heart failure; one which may lead to improved prevention and treatment. Audience: Clinical and experimental cardiologists will find the book a helpful source of ideas and inspiration. |
Contents
Role of tissue and circulating substance P in cardiovascular injury associated with | 9 |
Interventions in experimentally induced diabetic cardiomyopathy | 31 |
Experimental models | 47 |
Copyright | |
32 other sections not shown
Other editions - View all
Pathophysiology of Heart Failure Naranjan S. Dhalla,Pawan K. Singal,Nobuakira Takeda,Robert E. Beamish Limited preview - 2012 |
Pathophysiology of Heart Failure Naranjan S. Dhalla,Pawan K. Singal,Nobuakira Takeda,Robert E. Beamish No preview available - 2011 |
Pathophysiology of Heart Failure Naranjan S Dhalla,Pawan K Singal,Nobuakira Takeda, MD, PhD No preview available - 1995 |
Common terms and phrases
acid action potential activity adenylyl cyclase alloxan alterations animals antioxidant ATPase bFGF binding Biochem Biol Chem blood Ca² Ca2+ channel Ca2+-ATPase calcium calreticulin CaM kinase cardiac muscle cardiomyocytes cardiomyopathy Cardiovasc Res cardiovascular catecholamine cellular changes chronic Circ Res collagen concentration contractile coronary artery creatine kinase decreased diabetic rats disease dysfunction effects endothelin enzyme exchange experimental factor figure free radicals function glucose glutathione hamster heart cells heart failure hormones hypertension hypertrophy hypoxia Ica(L increased induced inhibition inhibitor inotropic insulin intracellular ischemia ischemic isolated isoproterenol left ventricular levels mechanism mediated membrane metabolic Mol Cell Cardiol muscle cells myocardial infarction myocardium myofibrillar myofibrils myosin Na,K-ATPase oxide oxygen pathway patients perfusion Pharmacol phospholamban phosphorylation Physiol plasma pressure rat heart receptor reduced regulation release reperfusion response role sarcolemmal sarcoplasmic reticulum significantly skeletal muscle smooth muscle stimulation studies synthesis tissue vascular WKY rats