Bacterial Resistance to Antimicrobials

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Richard G. Wax, Kim Lewis, Abigail A. Salyers, Harry Taber
CRC Press, Nov 21, 2001 - Science - 528 pages
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Focuses on combating bacterial pathogens by understanding their strategies of defense!

Each chapter begins with a summary of concepts, so those not actively working in the field gain an overall picture of what follows!

Highlights antibiotic resistance in pathogens that poses the greatest threat to human health!

Containing nearly 2000 references for additional research, Bacterial Resistance to Antimicrobials
  • discusses the ecology of drug resistance genes, acquired response, and selection in natural bacterial populations
  • describes global response systems that are a basis of resistance
  • details antibiotic modification, inactivation, and host target modification as means of resistance development
  • considers efflux mechanisms, one of the major causes of multidrug resistance
  • covers concepts for developing therapies against multidrug resistant organisms
  • emphasizes the structural basis of lactamases and other enzymes involved in inactivation of antibiotics
  • surveys the epidemiology of methicillin resistance among nosocomial isolates and community-acquired strains
  • outlines molecular detection methods for mainstream diagnostic tests
  • assesses the promise of modern genomics to identify novel targets for drug discovery screening

    Presenting the molecular basis, methods of detection and identification, and concepts for reducing the development and spread of resistant bacterial strains, Bacterial Resistance to Antimicrobials is an excellent reference for microbiologists, pharmacists, public health officials, infectious disease specialists, organic and medicinal chemists, and upper-level undergraduate and graduate students in these disciplines.
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    Contents

    V
    1
    VI
    19
    VII
    37
    VIII
    61
    IX
    91
    X
    123
    XI
    161
    XII
    193
    XV
    239
    XVI
    265
    XVII
    295
    XVIII
    331
    XIX
    355
    XX
    405
    XXI
    427
    XXII
    455

    XIII
    209
    XIV
    223

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    About the author (2001)

    Kim Lewis is the author and illustrator of many picture books and is best known for her popular series featuring Floss the sheepdog. Her artwork is inspired by the Northumberland countryside, where she lives.

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