Effects of Sex Differences and Hippocampal Lesions on Exploratory Behaviors and Wayfinding Performance in Rats in a Novel Environment: A Research Report Submitted in Partial Fulfillment ...University of Michigan, 1987 - Brain |
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animals with bilateral animals with HPC animals with right ANOVA behaviors and wayfinding bilateral hippocampal lesions bilateral HPC lesions bilateral lesions cognitive map control animals control rats Day 4 X+S.D. degree of directional degree of heading differences in frequency differences in swim directional heading error disoriented individuals estrous cycle exploration and wayfinding exploratory activity exploratory platform activity female rats find the platform frequency of exploratory frequency of rearing groups of animals hippocampal damage incidence of rearing jumping Kolb landmarks left hemisphere lesioned animals lesioned group male and female Mean Frequency Morris tank Morris water tank navigation novel environment O'Keefe and Nadel platform quadrant quadrant selection quadrant Y rearing behavior right hemisphere right HPC lesions Scheffe allowances sex differences significant differences spatial learning suggests swim distance Therrien total platform activity trials visual cues wayfinding ability wayfinding performance Whishaw X+S.D. range