Tumor markers: biology and clinical applications
Tumor markers, or antigens, are subtances produced in the body by malignant tumors. Their detection is useful in both diagnosing cancer and monitoring therapy. This straight-forward book provides a comprehensive overview designed to assist physicians who deal with cancer patients. The contributions by leading authorities include discussions of techniques for detecting tumor markers, steroid receptors, monoclonal antibodies, flow cytometry, chromosomal abnormalities, radioimmunodetection, ectopic hormones, cell markers in leukemia, nucleolar antigens, and non-specific markers.
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4? Enzymes as Markers
Steroid Hormone Receptors as Tumor Markers
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ABO H acid phosphatase activity adenocarcinoma analysis antisera antiserum assay benign biochemical bladder cancer blood group breast cancer Busch cancer patients Cancer Res carcinoembryonic antigen carcinoma cell lines cell surface antigens characterization chromosome chromosome changes Clin clinical colorectal correlation Cytogenet dehydrogenase demonstrated detection diagnosis disease elevated enzyme epitopes estrogen extracts fetal flow cytometry gastric gastrointestinal glycolipid glycoprotein Hakomori S-i hepatoma hormone human cancer human tumors Immunol immunologic immunoperoxidase incubated isoenzymes Javadpour karyotypic LD isoenzymes leukemia levels liver lung lymph nodes lymphocytes lymphoma malignant melanoma metastatic monoclonal antibodies mucin mucosa Natl neoplastic ng/ml normal tissues Novikoff hepatoma nucleolar antigens nucleolar fluorescence nucleoli ovarian pancreatic peptide presence primary prognosis prostate cancer proteins purified radioimmunodetection seminoma sensitive sera serum specific stage staining structure studies synthesis Table techniques testicular cancer therapy translocation tumor cells tumor markers tumor tissue tumor-associated antigens