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abnormal genes affected children Anencephaly antibodies babies Barr bodies blood group incompatibility brain carried carrier cataract cause mental cause of mental cerebral palsy chemical child colleagues condition damage developed diet difficulty disease ditions Down's syndrome enzyme example extra chromosome fact factors feebleminded female forms of mental Fountain Hospital genetic heredity humans Hurler's syndrome Hydrocephalus imbecility important inherited intelligence quotient kernicterus Kirman Klinefelter's syndrome known large number less level of intelligence liable London low birth weight males malformations Mendelian recessive meningitis mental backwardness mental defect mental handicap mental retardation mentally subnormal mother needed nervous system normal number of children ovum parents patients Penrose phenylalanine phenylketonuria population possible pregnancy prematurity rate prevalence prevent problem produce published reported result Rhesus negative Rhesus positive risk seems severely subnormal sex cells social Spina Bifida survey survive technique tion translocation treatment triple-X triple-X syndrome tuberous sclerosis twin urine usually whilst X chromosomes