Cellular and Molecular Immunology
The book provides a synthesis and critical analysis of advances in the field of cellular and molecular immunology, and aims to help the reader review the respective literature from the proper perspective. It offers material on the functional anatomy of immune responses, including regional immunity such as the cutaneous and mucosal immune systems. This third edition covers advances in the knowledge of the structures of molecules involved in immune responses, signal transduction, and lymphocyte apoptosis, and the development and functions of immune cells as revealed by the application of transgenic and knockout mouse models. The book is intended for medical school immunology courses, undergraduate and graduate immunology courses.
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PRESENTATION TO T LYMPHOCYTES
B CELL ACTIVATION AND ANTIBODY
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adhesion alleles amino acid anti antibody antigen antigen receptors APCs autoimmune bacteria binding blood bone marrow called CD4+ T cells cell activation cell surface cell-mediated immunity cellular Chapter class II MHC clones complement costimulators CTLs cules cytes cytokines cytoplasmic dendritic cells differentiation disease domains effector encoded endothelial cells enzymes factor foreign antigens function genes graft heavy chain helper T cells human IFN-y immune responses immune system Immunology induced infections inhibit innate immunity integrins interactions intracellular isotype kinase leukocytes ligand light chain lymph nodes lymphocytes lymphoid lysis macrophages mast cells mature mechanisms mediated membrane memory T cells MHC molecules mice microbes mouse mutations neutrophils NK cells normal pathway peptides phagocytes phagocytosis plasma production protein antigens proteins reactions rearrangement recognize regions residues role sequences signals specific immune sponses stimulate synthesis target cells thymocytes tion tissues transcription transplantation tumor tumor cells viral virus