penetrating into animated bodies, destroyed or mo dified their texture in different manners, which produces a diftinction of burns into three kinds.

In the firft, puftulesand redneiles are produced on the fkin, and the epidermis and fkin are frequently feparated.

In the fecond are formed Hydatides, where water is found- between the epidermis and Ikin, which caufes veficles of different fizes.

The third, fort where the fkin is fcorched, dried, and chopt.

The Volatile Alkali is to be ufed in three different ftates, according to the fpecies of burns. In the, firft and third fpecies, it is fufficient to apply to the burn a comprefs of the ftrongerb Volatile Alkali Fluor; the pain immediately ceafcs, and commonly in eight or ten minutes there does not remain the leaft veftige of them.

Some glafs of Borax in fufion having one day dropped upon my ringers, the fkin was fo much burned, that a rifing was formed like a wart. I immediately applied fome Fluor Volatile Alkali, and in half an hour I was at eafe: 1 remarked, that inftead of the rifing there was a cavity in the mufcles of the fingers which had been burned.

The fecond fpecies, which I have faid is accompanied with Hydatides, is comrrjnly caufed by boiling water. Here it is proper to break the G 2

bladders, after which apply comprefies with water mixed with Volatile Alkali Fluor: the proportion is about two drachms of Volatile Alkali to about an Englifh quart of water. Thefc compix-fles are renewed thrice a day, and in a very little time the cure.is compleated.

The- burn caufed by Kunckcl's Rhofphorus is very painful; the edges of it beobme callous, from the phofphoric acid being very much concentrated and intimately combined with the phlogilton: this burn top is e?.fed and cured by an immediate application of the Volatile Alkali.

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The vitriolic acid being cf a!i others the hcavieft next to the phofphoric, its effects upon the animal or vegetable texture bear the greatelt analogy to a burn.

One day I was auk ward enough to throw fome oil of vitriol on my face; that inftant it was covered with white puftules, which gave me exceffive ppiin. I wnfhed my face in water, and the anguifh abatrd; but next day it v/as covered with a yellowifh fcab, which would not have been trie • cafe had I ufed an Alkaline water, fuch as I have mentioned above.

From this theory of burning I am induced to think, that Volatile Alkali might be employed

with with fuccefs in the Coiips-de-Soleil; but having never tried ir, I muft leave the proof of that conjecture to experience.

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VIII.

Volatile Alkali Successfully Employed m

Canine Madness.

OF all the evils by which mankind is afflicted, perhaps the nature and character of Canine Madnefs are leaft known (f). It is believed that no human creature was ever feized with it, except from the bite of fome mad animal. It has even been remarked, that the poifon is communicated by the faliva, and that the wounds made thro' the cloaths are lefs dangerous than thofe made in the bare fkin: the realbn is, that in the firft cafe the ftuff partly cleans the teeth of the animal. In general it is obferved, that the greater progrefs the madnefs has made, the more difficult and obftinate is its cure.

(f) We are indebted to Mr. Lafibne for an excellent method of treating canine madnefs. That learned phyfician fays, that this dreadful diftemper is one of thofe with whofe nature and chara&er we are Icaft acquainted.

When

When a pcrfon is bit by a mad animal, the wound heals fometimes as eafily, as if it had not been envenomed; but fome time after, and the time varies from three weeks to three months, a dead pain begins to be felt in the part that was wounded; the fear fwells, grows red, opens again, and difcharges a reddifh, fetid, acrid humour. The patient is then feized with melancholy, indolence, and a general torpor, accompanied with almoft continual chillincfs, a difficulty of breathing, and unceafing anguifh; the pulfe is weak and irregular, the fleep difturbed, unquiet, broken with frightful dreams, ftartings, terrors; fometimes a pain is felt in the throat: this is the firft ftage of the diftemper, or what is called by the French, Rage mue.

The fecond ftage, or confirmed maanefs, called by them Rage blanche, is accompanied with the following fymptoms: The patient is. prefied with a burning thirft, and drinking is painful to him; he foon contracts a hatted for all liquids, particularly water, and a few hours after abhors it: his urine grows thick and hot, and fometimes is fuppreficd; his voice becomes hoarfe, and is often entirely loft; the patient is feized with fits of delirium intermingled with furious madncls, on which occafions he attempts

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to bite. When the diforder is come to this pitch, it is commonly regarded as incurable.

If we examine the different methods ufed in the treatment of canine madnefs, we mail find thofe hitherto moft fuccefsful where Volatile Alkali has been applied. Mr. Tiffot in his Advice to the People, page 219, fays, That a boy in whom the fymptoms of the madnefs began to fhew themfelves, was entirely cured by giving him fome dofes of Eau de Luce, and rubbing the parts adjacent to the wound with olive-oil in which camphire and opium had been diflblved;

Mr. de LafTone, an eminent phyfician, and member of the Royal Academy of Sciences, publifhed in 1776,' a method for curing canine madnefs, in which he recommends, as one of the moft efficacious remedies, a dofe of twentyfour drops of Volatile Alkali Fluor, to be taken inwardly twice a-day. The reader will fee with pleafure the fuccefs of this method in the work of Mr. de Laflbne, and the obfervations of Mr. Slats (g).

Cg) Mr. Blais, phyfician at Cluny, has (hewn his philanthropy in the horrible ravages committed in feveral village*of the Maconnois by a mad wolf: the fnccefs of his method does him the greateft honour.

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