Girls are disappearing in Botswana. The rumor is they're being harvested for muti, a witch doctor's potion traditionally derived from plants and animals—and which, some believe, can be made more potent by adding human remains. Detective David "Kubu" Bengu joins the investigation with the police force's newest detective—and only woman—Samantha Khama, for whom the case is personal.
Soon one girl's father, convinced that his daughter's death is linked to the recent popularity of a political candidate, takes the law into his own hands. After the father flees, what Kubu and Samantha find in the politician's home confirms their worst fears: muti containing human DNA is real.
Now Kubu and Samantha are thrust into a harrowing race to stop a serial killer or killers—and those who would pay for their special, lethal muti.