Corticobasal Ganglionic Degeneration: Cognitive and Functional Aspects (Google eBook)
Nova Publishers, Jan 1, 2005 - Medical - 143 pages
The clinical syndrome of asymmetric parkinsonism associated with cortical abnormalities along with peculiar pathology come to be known as corticobasal ganglionic degeneration (CBGD), actually defined simply as corticobasal degeneration (CBD). The definition of the clinical syndrome of CBD is still evolving. Ideally, the complete and accurate characterisation of the clinical syndrome is contingent on diagnosing all subjects who have the disease and excluding subjects who do not. The apparent rarity of the disease makes it a formidable task to accumulate a sufficient number of cases to analyse and obtain meaningful results, as well as making it difficult for physicians to gain familiarity with and to recognise the syndrome. The aim of this work will be to determine the nature of CBD, its clinical impact and its cortical involvement, by evaluating functional imaging and cognitive neuropsychological evaluation.
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2005 Nova Science abnormalities activation affected hand alien limb astrocytes asymmetric atrophy attention basal ganglia bilateral body schema Brain Res CBD patients cells cerebellar cerebellum cerebral cingulate cognitive complex contralateral corticobasal degeneration Coslett deficits diagnosis of CBD DLPFC errors execution eye field eye movements f-MRI fibers frontal dementia frontal lobe functional ganglionic degeneration gesture Goldberg gyrus Heilman human ideomotor apraxia imaging impaired inferior parietal intraparietal involved Kalaska Kertesz lesions limb apraxia Litvan metabolism monkey motor act motor cortex movement disorders myoclonus neglect Neurology neurons neuropsychological Paola Torre parietal areas parietal lobe parietal regions Parkinson's disease pathologic patients with CBD Pick's disease Pierrot Deseilligny pontine nuclei posterior parietal cortex posture premotor progressive supranuclear palsy projections receptive fields representation Rizzolatti Rothi saccade sensory sequence somatosensory stimuli studies subcortical suggest sulcus superior colliculus supplementary motor area syndrome target temporal thalamus University of Trieste
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