Transition Metals in the Synthesis of Complex Organic MoleculesThis text is designed as an easy access to the field of organotransition metal chemistry for advanced undergraduate and graduate students without a background in inorganic chemistry. The book first covers the basics of transition metal chemistry, giving a practical introduction to organometallic reaction mechanisms. The organic chemistry of transition metals is then presented, with many examples of applications in the synthesis of natural products, pharmaceuticals, polymers and materials. |
Contents
Organometallic Reaction Mechanisms | 13 |
Synthetic Applications of Transition Metal Hydrides | 39 |
Synthetic Applications of Complexes Containing MetalCarbon | 57 |
Synthetic Applications of Transition Metal Carbonyl Complexes | 123 |
Synthetic Applications of Transition Metal Carbene Complexes | 143 |
Synthetic Applications of Transition Metal Alkene Diene and Dienyl | 187 |
Other editions - View all
Transition Metals in the Synthesis of Complex Organic Molecules Louis S. Hegedus Limited preview - 1994 |
Common terms and phrases
acetate acid acyl aldehydes alkenes alkenyl alkyl alkynes allylic amines Angew anionic arene aryl asymmetric induction bond carbanions carbene complexes carbon monoxide catalyst catalyze cationic Chem chiral chlorides cleavage CO)5 Cr CO₂Me CO₂R complexes Eq compounds Comprehensive Organometallic Chemistry conjugated coordination coupling Cp2Zr cyclization cycloaddition cyclopropanation diene efficient electron electron-rich electrophilic Engl enol enones esters face opposite Figure halides Hegedus hydride hydrogenation insertion intramolecular ketones L4Pd ligands MeO2C MeOH metal carbonyl metal complexes metal-carbon metathesis nucleophilic attack OH OH olefin OMe OMe opposite the metal optically active organic synthesis Organomet Organometallic Chemistry OTBS OTMS oxidative addition palladium palladium(II Pd(II Ph Ph phosphine PPh3 produce react reaction reactivity reagents reductive elimination regioselectivity resulting species stable stereochemistry substitution substrates Synlett synthetic Tetrahedron Lett Transition Metal transmetallation tricarbonyl Trost undergo unsaturated yield