30th Hemophilia Symposium Hamburg 1999: HIV Infection and Epidemiology in Hemophilia; Gene Therapy in Hemophilia A and B; Therapy of Hepatitis C; Inhibitors in Hemophilia; Long-term Results after Joint Replacement; Pediatric Hemostasiology; Case Reports

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I. Scharrer, W. Schramm
Springer Science & Business Media, Oct 26, 2000 - Medical - 428 pages
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This book contains the contributions to the 30th Hemophilia Symposium, 1999. The main topics are HIV infection, inhibitors in hemophilia, modern treatment of hemophilia, drug-induced thrombophilia and pediatric hemostasiology. The volume is rounded off by numerous free papers and posters on hemophilia and associated topics.
 

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Contents

HIV Infection and Epidemiology in Hemophilia
1
in Hemophilia Patients in Germany Inquiries 1999
3
Gene Therapy in Hemophilia
11
GenotypePhenotype Correlation in Hemophilia A
13
Therapy of Hepatitis C
23
Current Therapy of Hepatitis C Virus Infection
25
Interferon Alpha2a Treatment in Patients with Hepatitis C and Bleeding Disorders
32
Report on Experience in the Treatment of Hepatitis C in HIVCoinfected Hemophiliacs
35
TwentyTwo Novel Mutations of Factor VII Gene in Factor VII Deficiency
235
Prevalence of Common Mutations and Polymorphisms of the Genes of FII FV FVII FXII FXIII MTHFR and ACEIdentified As Risk Factors for Veno...
240
Factor V VariantsFV LeidenFV R2 Polymorphism ex 13 FV Ddel Polymorphism int 16Risk Factors for Venous Thrombosis? Results of a Pilot Study
261
Relation Between Prothrombin Mutation 20210 GA Prothrombin Time Factor V Leiden and Prothrombin Level
266
Localization and Characterization of Mutations Within the Factor VIII Gene in a Cohort of 212 Patients with Hemophilia A
270
Genomic Diagnosis of Hemophilia A in Hungarian Patients
273
of Hungarian Hemophilia B Patients
277
d Poster Pediatrics
281

Inhibitors in Hemophilia
43
A New Therapeutic Option for Inhibitor Elimination in Patients with Acquired Hemophilia
45
LongTerm Results After Joint Replacement
53
LongTerm Results After Total Knee and Total Hip Replacement in Hemophilic Arthropathy
55
Total Knee Prosthesis in Hemophiliacs with Multilocular Hemophilic ArthropathyThe Zurich Experience
62
Corrective Osteotomy of the Lower Extremity in Hemophilic Arthropathy of the Knee and Hip Joint
65
Pediatric Hemostasiology
71
Anticoagulant Action of Activated Protein C is Diminished by Alpha2Macroglobulin in Newborn Plasma
73
Functional Consequences of Differences in Carbohydrate Sequences of Fetal and Adult Plasminogen and Fibrinogen
86
Hereditary Thrombophilic Risk Profiles in Children with Spontaneous Venous Thromboembolism
102
A Prospective 23Year FollowUp
110
HIT Type II without Thrombocytopenia in a 15YearOld Boy with Protein S Deficiency and Recurrent Deep Vein Thrombosis
114
Free Lectures
117
Modified BonnMalmö Protocol
119
A Novel Type of Mutation at the Propeptide Cleavage Site Ala+1Thr Causing Symptomatic Protein C Type II Deficiency
126
Lithuanian Hemophilia A and B Register Comprising Phenotypic and Genotypic Data
132
Greifswald Hemophilia B Study
144
Successful Treatment of Patients with von Willebrand Disease Using a HighPurity Double Virus Inactivated FVIIIvWF Concentrate IMMUNATE
154
Research Cooperation
161
Opportunities and Limits of ThirdParty Funding
163
a Poster Hemophilia
177
Experience with Recombinant Factor IX Benefix in Pediatrics
179
Articular Cartilage Is More Susceptible to BloodInduced Damage in Young Than in Old Age
182
Chronic Liver Disease in Hemophilia Patients
187
Coincidence or Genetics?
191
Description of a Retrospective CrossSectional Multicenter Trial
194
Results of a Survey Carried Out for the Associations Tenth Anniversary
197
Alpha Tocopherol A Meditation with Few Side Effects for Treating Pain in Patients with Hemarthrosis
199
Neurosensorial Sequelae in Hemophilia
202
b Poster Thrombophilia
207
Effect of Vitamin Supplementation in Venous Thrombosis Patients with Hyperhomocysteinemia
209
Therapy and Prophylaxis of the Thromboembolic Syndrome in Pregnancy and Post Delivery
214
Is Factor V Leiden Associated with an Increased Risk for Fetal Loss?
217
c Poster Molecular Biology
223
Evidence for a Defective Vitamin KEpoxideReductase Complex
225
and Metabolic Risk Factors for Coronary Heart Disease in Obese Children and Adolescents
283
Inverse Correlation Between Thyroid Function and Hemostatic Risk Factors for Coronary Heart Disease in Obese Children and Adolescents
292
HeparinInduced Thrombocytopenia Type II in Three Children and Anticoagulant Therapy with Org 10172 Orgaran
299
Heparin Concentration Activated Clotting Time and Markers of Coagulation Activation During Pediatric Heart Catheterization
303
Therapeutic Options in Immune Thrombocytopenic Purpura in Childhood
307
Camps for Children and Young Adults with Hemophilia in Germany Austria and Switzerland
313
Clinical Experience with the PFA100 System in Children and Adolescents
317
Endothelial Activation Markers in Health and DiseaseBig Endothelin1 and Endothelin1 in Children
321
e Poster Case Reports
331
Dramatic IntraAbdominal BleedingFirst Symptom of Hemophilia B in a Neonate
333
Successful Therapy with Administration of Recombinant Factor VIIa
336
Continuous Infusion of Recombinant FIX BeneFIX During Herniotomy in an Infant
342
Clinical Course of Intramuscular Bleeds in a Patient with Factor XIII Deficiency
345
Immunthrombocytopenia and Lupus Antibodies in a Patient with Hemophilia A
347
Cerebral Sinus Thrombosis after Asparaginase Therapy
350
f Poster Hemorrhagic Disorders
354
506 Mutation and the G20210A Prothrombin Mutation
355
Acquired Hemophilia in Women Postpartum
358
Elevated Lpa Level and Heterozygous Factor V Mutation FV 1691 AG a 26YearsOld Female with Ischemic Colitis
361
Modulation of Antigens of Neutrophil Granulocytes by Extracorporal Apheresis
365
Glycoprotein IIbIIIa Receptor Antagonist c7E3 Fab and Anticoagulants Show an Additive Effect on Thrombinlnduced Platelet Aggregation after Hig...
369
BetweenDrug Comparison of the Effect of Ticlopidine and Acetylsalicylic Acid on Platelets in an In Vitro Circulation Model
378
A Flow Cytometric Assessment
380
Flow Cytometric Comparison of Platelet Activation During PTCA Stent Implantation and Rotablation
382
Analysis of Hemostatic Capacity before and after Extracorporal PlateletPheresis by the PFA100 Test System
384
Heparin Coating of Coronary Stents Increases Time Until Stent Occlusion Due to Delayed Platelet Activation in an In Vitro Circulating Model
388
HighSpeed Detection of Human Progenitor Cells HPC to Support the Timing of Aphereses
390
SemiAutomated Flow Cytometry Can Help in Timing the Onset of a StemCell Leukapheresis
394
g Poster Diagnostic Problems
399
Determination of FXIII Activity in Fibrin Glues and FXIII Concentrates and Measurement of HeparinAT Complexes in FVIII Products
401
Comparison of BVDV and SFV Used as Models for Hepatitis C Virus in Virus Validation Studies
408
Preoperative Coagulation Screening in Children Focused on PTT Elevation
417
Resonance Thrombographic Analysis of Coagulation Status after Transfusion of Platelet Concentrates with Different Storage Times
420
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