A Color Atlas of Comparative Pathology of Pulmonary Tuberculosis

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Franz Joel Leong, Veronique Dartois, Thomas Dick
CRC Press, Apr 19, 2016 - Medical - 236 pages
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An annual death toll of 2 million, coupled with rising drug resistance, highlights the need for the development of new drugs, better diagnostics, and a tuberculosis (TB) vaccine. Addressing these key issues, A Color Atlas of Comparative Pathology of Pulmonary Tuberculosis introduces TB histopathology to the non-histopathologists, students, scientists, and doctors working, learning, and teaching in the field of TB. It contains 100 color photographs and illustrations that bring clarity to the information presented.

The atlas takes the unusual approach of covering multiple species histopathology, arguably the first and quite possibly the only resource to do so. It provides a simple, annotated, and visual presentation of the comparative histopathology of TB in human and animal models. The editors have compiled information that helps TB scientists to distinguish between the features of all major animal models available and to use them with their strengths and limitations in mind. The book provides guidance for selecting the best animal model(s) to answer specific questions and to test the efficacy of drug candidates.

 

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Contents

Drug Discovery forNeglected Diseases of the Developing World
3
Tuberculosis Biology and Drug Discovery
13
Immunopathology ofTuberculosis Disease across Species
19
II
29
Anatomy and Histology of the Human Lung
31
Pathology of Tuberculosis in the Human Lung
53
Pulmonary Tuberculosis in Monkeys
83
Pulmonary Tuberculosis in the Rabbit
107
Pulmonary Tuberculosis in the Guinea Pig
131
Pulmonary Tuberculosis in the Rat
157
Pulmonary Tuberculosis in the Mouse
175
Glossary
195
Back cover
209
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