A Life of Ernest Starling

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Academic Press, Aug 6, 2010 - Science - 227 pages
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Ernest Starling (1866-1927) was pre-eminent in the golden age of British Physiology. His name is usually associated with his “Law of the Heart, but his discovery of secretin (the first hormone whose mode of action was explained) and his work on capillaries were more important contributions. He coined the word 'hormone' one hundred years ago. His analysis of capillary function demonstrated that equal and opposite forces move across the capillary wall--an outward (hydrostatic) force and an inward (osmotic) force derived from plasma proteins.

Starling’s contributions include:
*Developing the "Frank-Starling Law of the Heart," presented in 1915 and modified in 1919.
*The Starling equation, describing fluid shifts in the body (1896)
*The discovery of secretin, the first hormone, with Bayliss (1902) and the introduction of the concept of hormones (1905).
 

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Contents

Prelude
3
Chapter 1 Hearts and Capillaries
13
Chapter 2 18901899
40
Chapter 3 Secretin Politics and the New Institute
52
Chapter 4 Starlings Law and Related Matters
77
The Haldane Commission 191013
99
Chapter 5 The Great War
105
Chapter 6 19181920
122
Chapter 7 Back to Research
137
Chapter 8 The End of the Trail
155
Chapter 9 A Life Surveyed
171
Appendix I Starlings Publications
187
Appendix II Publications from the Department of Physiology UCL 18991927 Starlings Years
197
Annotated Bibliography
201
Index
215
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