A Practitioner's Guide to Prescribing Antiepileptics and Mood Stabilizers for Adults with Intellectual Disabilities

Front Cover
Jose de Leon
Springer Science & Business Media, Mar 2, 2012 - Medical - 507 pages

Emotional, behavioral, and neuropsychiatric conditions are common in individuals with intellectual disabilities (IDs), most notably epilepsy, aggression, self-injurious behaviors, and bipolar and other mood disorders. Despite the prevalence of such problems, there is a scarcity in the literature of reliable information on medical treatments for those with IDs.

A Practitioner's Guide to Prescribing Antiepileptics and Mood Stabilizers for Adults with Intellectual Disabilities provides a detailed framework for prescribing for this challenging population. Featuring the most up-to-date information on factors that inform prescribing, the Guide addresses basic issues and controversies (e.g., the rift between evidence-based and personalized medicine) in treating adults with cognitive deficits. Clients' specific needs are emphasized in developing appropriate and effective pharmacological intervention for improved outcomes and quality of life. Drugs discussed in the Guide include carbamazepine, clonazepam, diazepam, ethosuximide, felbamate, gabapentin, lacosamide, lamotrigine, levetiracetam, lithium, lorazepam, oxcarbazepine, phenobarbital, phenytoin, pregabalin, primidone, rufinamide, tiagabine, topiramate, valproate, and zonisamide. For each of these compounds, the guidelines cover:

  • Indications for use; relative and absolute contraindications.
  • Assessment during treatment; therapeutic drug monitoring; warning signs and symptoms for caretakers.
  • Dosage: administration; initial and maximum recommended dosage; modifications associated with drug-drug interactions, personal characteristics, and (where appropriate) genetic variations.
  • Adverse drug reactions: common, relatively uncommon, and potentially lethal, plus risk of metabolic syndrome.
  • Guidelines for discontinuation.
  • References, tables, and drug utilization reviews.

A Practitioner's Guide to Prescribing Antiepileptics and Mood Stabilizers for Adults with Intellectual Disabilities is an indispensable decision-making reference for psychiatrists, neuropsychologists, psychopharmacologists, neurologists, internists, and clinical psychologists.

 

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Contents

Chapter 1 Introduction
1
Chapter 2 A Practitioners Guide to Prescribing Carbamazepine for Adults with Intellectual Disabilities
19
Chapter 3 A Practitioners Guide to Prescribing Clonazepam for Adults with Intellectual Disabilities
55
Chapter 4 A Practitioners Guide to Prescribing Diazepam for Adults with Intellectual Disabilities
75
Chapter 5 A Practitioners Guide to Prescribing Ethosuximide for Adults with Intellectual Disabilities
95
Chapter 6 A Practitioners Guide to Prescribing Felbamate for Adults with Intellectual Disabilities
107
Chapter 7 A Practitioners Guide to Prescribing Gabapentin for Adults with Intellectual Disabilities
123
Chapter 8 A Practitioners Guide to Prescribing Lacosamide for Adults with Intellectual Disabilities
138
Chapter 14 A Practitioners Guide to Prescribing Phenobarbital for Adults with Intellectual Disabilities
279
Chapter 15 A Practitioners Guide to Prescribing Phenytoin for Adults with Intellectual Disabilities
302
Chapter 16 A Practitioners Guide to Prescribing Pregabalin for Adults with Intellectual Disabilities
333
Chapter 17 A Practitioners Guide to Prescribing Primidone for Adults with Intellectual Disabilities
349
Chapter 18 A Practitioners Guide to Prescribing Rufinamide for Adults with Intellectual Disabilities
366
Chapter 19 A Practitioners Guide to Prescribing Tiagabine for Adults with Intellectual Disabilities
381
Chapter 20 A Practitioners Guide to Prescribing Topiramate for Adults with Intellectual Disabilities
395
Chapter 21 A Practitioners Guide to Prescribing Valproate for Adults with Intellectual Disabilities
419

Chapter 9 A Practitioners Guide to Prescribing Lamotrigine for Adults with Intellectual Disabilities
155
Chapter 10 A Practitioners Guide to Prescribing Levetiracetam for Adults with Intellectual Disabilities
185
Chapter 11 A Practitioners Guide to Prescribing Lithium for Adults with Intellectual Disabilities
206
Chapter 12 A Practitioners Guide to Prescribing Lorazepam for Adults with Intellectual Disabilities
235
Chapter 13 A Practitioners Guide to Prescribing Oxcarbazepine for Adults with Intellectual Disabilities
255
Chapter 22 A Practitioners Guide to Prescribing Zonisamide for Adults with Intellectual Disabilities
461
Chapter 23 A Practitioners Guide to Prescribing Nonoral Antiepileptics for Adults with Intellectual Disabilities
481
Chapter 24 Conclusion
486
Index
491
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