A Primer of Chemical PathologyThis book has been written primarily for medical students and junior doctors in clinical practice, but would also be a useful reference for postgraduate students in chemical pathology (clinical biochemistry), laboratory scientists, pathologists and medical laboratory technologists. It covers the field of chemical pathology, the biochemical basis of disease, and provides a basic understanding of the relationship between abnormal biochemical test results and disease states. A rational approach to proper selection and interpretation of biochemical investigations is adopted for each organ system or analyte covered in the 28 chapters. Emphasis is placed on areas and problems most commonly met with in clinical practice. Meant primarily as an introductory study book to the subject rather than as a reference text, the materials have been presented in a clear, condensed format to aid the study process. The written text is amply supplemented with relevant illustrations. |
Contents
SODIUM AND WATER METABOLISM | 1 |
Hypergammaglobulinaemia 170 | 4 |
Hypomagnesaemia contd | 10 |
Mineralocorticoid excess syndromes | 11 |
Hyponatraemia | 18 |
Mineralocorticoid deficiency syndromes | 28 |
69 | 41 |
Disorders of the serum sodium | 75 |
Luteal phase menstrual cycle 265 | 227 |
Oxygen metabolism | 262 |
Hypergonadism | 269 |
Noradrenaline | 295 |
INHERITED METABOLIC DISEASES | 297 |
| 359 | |
| 363 | |
| 374 | |
Nephrotic syndrome 11 | 84 |
POTASSIUM | 88 |
Definitions | 103 |
Mixed disturbances | 111 |
Hyperglycaemia | 126 |
Neuroglycopaenia | 133 |
Nicotinamide 317 | 155 |
Lithocholic acid | 156 |
Hypergammaglobulinaemia | 170 |
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Common terms and phrases
abnormalities absorption ACTH activity acute adrenal albumin alcohol aldosterone amino acids anion gap assay associated bicarbonate bilirubin biochemical blood bone calcium cause cells cholesterol chronic clinical concentration cortisol creatinine decreased defect deficiency diabetes mellitus diagnosis diarrhoea disorders diuretics drug enzyme excess excretion extracellular factors fatty acids Figure fluid function gluconeogenesis glucose glycogen HCO3 hepatitis high plasma hormone hydrogen ions hypercalcaemia hypertension hypoglycaemia hypokalaemia hyponatraemia hypothyroidism increased renal inhibition insulin intake iron kidney Laboratory evaluation lactate lesions lipid lipoprotein liver disease loss magnesium malignancy marker metabolic acidosis metabolic alkalosis mineralocorticoid mmol/day mmol/L neonatal nephron normal occur oestrogens osmolality pancreatic patients Pco₂ phosphate pituitary plasma plasma levels porphyria potassium pregnancy primary produced protein reabsorption receptor renal failure respiratory result secretion serum sodium stimulation syndrome synthesis therapy thyroid tissue tubular tubule tumour urate urea urinary urine usually values vitamin VLDL