A Review of the Draft Report of the NCI-CDC Working Group to Revise the 1985 Radioepidemiological Tables

Front Cover

The National Research Council was asked by the Centers for Disease Control and Prevention (CDC) to review the draft report of the National Cancer Institute (NCI)-CDC's working group charged with revising the 1985 radioepidemiological tables. To this end, a subcommittee was formed consisting of members of the Council's Committee on an Assessment of the Centers for Disease Control and Prevention Radiation Programs and other experts. The original tables were mandated under Public Law 97-414 (the "Orphan Drug Act") and were intended to provide a means of estimating the probability that a person who developed any of a series of radiation-related cancers, developed the cancer as a result of a specific radiation dose received before the onset of the cancer. The mandate included a provision for periodic updating of the tables. The motivation for the current revision reflects the availability of new data, especially on cancer incidence, and new methods of analysis, and the need for a more thorough treatment of uncertainty in the estimates than was attempted in the original tables.

 

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Contents

EXECUTIVE SUMMARY
1
1 INTRODUCTION
3
2 SUMMARY OF THE SUBCOMMITTEES REPORT
4
4 TREATMENT OF ACUTE AND PROTRACTED CHRONIC EXPOSURES
8
5 ASSESSMENT OF TIMESINCEEXPOSURE AS A MODIFIER OF RISK
9
8 TREATMENT OF UNCERTAINTY
10
9 HOW SHOULD THE RADIOEPIDEMIOLOGICAL TABLES BE MADE AVAILABLE TO THE PUBLIC?
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10 FUTURE REVISIONS AND BROADER ISSUES
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11 CONCLUSIONS AND RECOMMENDATIONS
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12 SUGGESTIONS FOR FUTURE COMPENSATION POLICY
34
APPENDIX A Specific Comments on the Working Groups Draft Report
36
APPENDIX B Specific Comments on the Interactive RadioEpidemiological Program
38
APPENDIX C Supplement to Text
41
REFERENCES
46
Information on Committee Members
49
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