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50 per cent acute exacerbations acute respiratory illness asthma atmospheric pollution averages of minimum averages of smoke bacteriological Blyth and Bedlington breathless bronchial carcinoma bronchus chronic bronchitis cigarette smoking co-operation cough coughers cytological Day and Night days below 80 develop disease duration of symptoms Dyspnoea grades ELECTROCARDIOGRAMS eosinophiles evidence of emphysema Exacerbation groups F.E.V. change family history Fletcher forced expiratory volume grades on entry greater health visitor hypercapnia illness scores incidence of H incidence of pneumococcal influenzae and Str influenzae infection initial F.E.V. localized emphysema minimum temperatures Newcastle Morning mucopurulent myocardial ischaemia Newcastle upon Tyne Northumberland County number of exacerbations observation official records Ogilvie and Newell once dyspnoea organisms patients Phlegm habit pneumococcal infection pneumoniae pulmonary hypertension purulent Quarterly averages record of acute right ventricular hypertrophy severe exacerbations severity of exacerbation significant association significantly specimens of sputum sputum contained H sputum specimens TABLE tion ventilatory deterioration X-ray