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Review of Adult Renal Cystic Disease
Experimental Models of Cystic Kidney Disease
8 other sections not shown
acid adenyl cyclase animal treated antidiuretic hormone areas biphenyl cellular debris chronic drug treatment Clin collecting ducts concentrating ability concentrating defect control animals cortex cortical cuboidal epithelium cyclic adenosine monophosphate cyst formation cystic changes cysts decreased descending thin limb diameter diet dilated tubules diphenylamine distal convoluted tubule distal tubule drug-treated and control drug-treated animals electron microscopy epithelial cells experimental Figure fluid to plasma functional and morphologic glomerular filtration rate hypokalemia increased inner medulla interstitial fibrosis loop of Henle lumen male medullary cystic disease medullary sponge kidney morphologic changes Morphologic Studies mOsm./kg nephron normal nuclear observed osmolality osmotic outer medulla pathogenesis Physiol plasma inulin ratio polycystic kidney disease portion potassium pressure proximal convoluted tubule proximal tubule pyelonephritis regression renal concentrating renal cystic disease Santoquin showed significantly sodium tion tissue toxic tubular basement membranes tubular dilatation tubular fluid urea urine output water permeability weeks of drug