A Study of Anion Exchange (chloride-sulfate) in Red Blood Cells: The Effect of Sulfonamides |
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acetazolamide action activation energy added addition analysis anion anion transport assumed bicarbonate calculated carbonic anhydrase carrier caused cell membrane charge chloride concentration chloride-sulfate exchange compared concluded considered decrease determined difference diffusion drugs Effect Effect of acetazolamide electrode enzyme equation erythrocytes estimated exchange rate experiments explained external Figure final fluid followed FORMAT furosemide greater half hematocrit increase indicated inhibition inhibitors initial interaction isethionate Jacobs k₂ kcal/mole less Luckner 34 mean measured mechanism method minutes mixing Mond move movement observed occur Parpart Passow permeability Physiol plot pore postulated POTENTIAL present rapid rate constant rate of exchange reaction recorded red blood cells reduction reported result runs saline seconds SETS shown similar slopes sodium sodium sulfate solution Squares standard sucrose sulfanilamide sulfate suspension Table temperature volume change