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acid action acute agar agglutination agglutinins Amer anaerobic animals antibodies antigen appear autolysis Avery bacillus Bact bacteria bactericidal Bakt Biol blood blood-agar Brit broth culture c.cm C.R. Soc cells cent cocci coccus colonies described Deuts dilution diplococcus disease doses endocarditis enterococcus epidemic erysipelas evidence experimental exudate fermentation filtrates fluid gonococcus gonorrhoea Gram-negative growth guinea-pigs haemolysis haemolytic streptococci heated ibid immunity incubation infection InfektKr influenza bacilli inoculation intravenous investigated isolated klin Lancet large numbers lesions leucocytes Lond lung McLeod medium meningitis meningococcus method mice micro-organism Morgenroth nasopharynx normal observed obtained occur optoquine organisms Orig Path pathogenic patients pertussis Pfeiffer's bacillus pneumococci pneumonia present produced pure culture pyogenes rabbits reaction resistance respiratory scarlatina septicaemia sera serological serum showed similar sputum staphylococci strains subculture subcutaneous substance susceptible suspension temperature tissue toxic toxin V-factor vaccine viridans virulence Wschr X-factor