Absorbable and Biodegradable Polymers
Interest in biodegradable and absorbable polymers is growing rapidly in large part because of their biomedical implant and drug delivery applications. This text illustrates creative approaches to custom designing unique, fiber-forming materials for equally unique applications. It includes an example of the development and application of a new absorbable system, a condensed encyclopedia on novel PEG-based copolyesters, and the first comprehensive discussion of a novel class of absorbable tissue adhesives. The book also provides up-to-date information on important tissue engineering technologies and approaches to utilizing these technologies for long awaited practical applications.
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absorbable polymers absorbable tissue adhesives Absorbable/Biodegradable absorption agents amorphous applications bioactive biocompatibility biodegradable biological Biomater Biomaterials biomedical braided cancer carboplatin carriers cell chain chemical chemotherapy chitosan clinical co-workers composition Conclusion and Perspective controlled release copolyesters copolymers crosslinked crystalline crystallization cyanoacrylate cytokines degradation delivery systems devices diabetic dose drug delivery effect end-grafting evaluated fibers formulations gel-forming glucose glycol glycolide GM-CSF growth hyaluronic acid hydrogel implantation initial injectable insulin insulin release kinetics materials matrix mg/ml microparticles microspheres molecular weight molecules monofilament monofilament sutures monomers nonabsorbable paclitaxel Patent to Poly-Med patients PG-MP phase PLGA PLLA polyaxial polyesters polyglycolide polymeric polymers postoperative prepared produce properties rats release profile release systems response scaffolds segments Shalaby sodium hyaluronate spherulitic sterilization subcutaneous surface surgical sutures synthetic absorbable temperature therapy tion tissue adhesives tissue engineering toxicity Trapidil tumor U.S. Patent vascular grafts vitro vivo wound
Page 281 - WA, et al. Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4. Cell 1992; 71:1093-1102.