Acne and Its Therapy
Guy F. Webster, Anthony V. Rawlings
CRC Press, May 17, 2007 - Medical - 328 pages
Addressing one of the most commonly encountered conditions seen by the dermatologist, this source analyzes the pathophysiology, evaluation, diagnosis, clinical features, and control of acne. With full-color illustrations, this source delves into the available treatment options for difficult cases of acne and scarring and provides expert discussions of management regimens including topical and systemic therapies, laser treatments, and new medications.
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This book provides massive amount of information about Acne and Acne treatments not available elsewhere. It discusses the mechanism by which the treatments work in detail.
Chapter 2 Cell Biology of the Pilosebaceous Unit
Chapter 3 Sebum Secretion and Acne
Chapter 4 The Molecular Biology of Retinoids and Their Receptors
Chapter 5 Molecular Biology of Peroxisome ProliferatorActivated Receptors in Relation to Sebaceous Glands and Acne
Chapter 6 Antimicrobial Peptides and Acne
Chapter 8 Antimicrobial Therapy in Acne
Mechanism of Action Skin Delivery and Clinical Results
Chapter 13 The Effect of Sphingolipids as a New Therapeutic Option for Acne Treatment
Chapter 14 Reductase and Its Inhibitors
Active Delivery Formulation and Testing
Chapter 16 Targeted Delivery of Actives from Topical Treatment Products to the Pilosebaceous Unit
Chapter 17 Topical Therapy and Formulation Principles
Chapter 18 In Vitro Models for the Evaluation of Antiacne Technologies
Acad Dermatol acne lesions acne vulgaris activity adapalene androgen antibiotics antimicrobial Arch Dermatol azelaic acid bacterial benzoyl peroxide Biol cells cholesterol clinical comedones cosmetic culture Cunliffe WJ decrease delivery Dermatology differentiation Downing DT drug effect efficacy enzyme epidermis estradiol expression fatty acids follicular formulation gene hair follicle hormone human sebaceous glands human sebocytes human skin increased inflammation inflammatory acne inhibition Invest Dermatol keratin keratinocytes Kligman layer levels ligands lipid lipogenesis liposomes metabolism model sebum normal oral contraceptives pathogenesis of acne pathway penetration peroxisome proliferator peroxisome proliferator-activated receptor pilosebaceous pilosebaceous duct pilosebaceous unit PPAR PPARa PPARg Propionibacterium acnes protein reduced regulation retinoic acid role salicylic acid saturated sebaceous follicles sebaceous glands sebum sebum production sebum secretion skin surface steroid stratum corneum studies synthesis testosterone therapy Thiboutot tissue topical retinoids treatment of acne tretinoin triglycerides unsaturated vehicle vitro vivo wax esters Zouboulis CC
Page iii - We trust that this volume will be of broad interest to scientists and clinicians alike. Alan R. Shalita SUNY Health Science Center Brooklyn, New York iii Series Editors ALAN R.
Page iii - During the past decade there has been a vast explosion in new information relating to the art and science of dermatology as well as fundamental cutaneous biology. Furthermore, this information is no longer of interest only to the small but growing specialty of dermatology. Scientists from a wide variety of disciplines have come to recognize both the importance of skin in fundamental biological processes and the broad implications of understanding the pathogenesis of skin disease. As a result there...
Page iii - Over the past decade, there has been a vast explosion in new information relating to the art and science of dermatology as well as fundamental cutaneous biology. Furthermore, this information is no longer of interest only to the small but growing specialty of dermatology. Scientists from a wide variety of disciplines have come to recognize both the importance of skin in fundamental biological processes and the broad implications of understanding the pathogenesis of skin disease. As a result, there...