Acute Lung Injury
John J. Marini, Timothy W. Evans
Springer, 1998 - Medical - 463 pages
To integrate current knowledge in terms of basic and clinical science and to highlight problems, thirty world-renowned experts in the field of acute lung injury describe the state of up to date knowledge regarding the epidemiology, pathophysiology, and clinical management of acute lung injury. Novel techniques for the clinical support of these difficult patients are discussed in full. Prospects for successful pharmacological intervention are also outlined. This book is aimed at those practising within the field of critical care and is likely to become an indispensable aid to all concerned with the investigation and management of patients with severe respiratory failure.
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Prognostic Factors and Outcome of ALI
Cytokines and Lung Injury
Complement and Endotoxin in Lung Injury
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activation acute lung injury acute respiratory failure adult respiratory distress airspaces airway pressure alveolar epithelial alveoli Appl Physiol ARDS ARDS patients associated breathing chest wall clinical trials cmH2O collapse compliance concentration cytokines decrease disease dose effects endotoxin epithelial barrier EVLW experimental extracorporeal factors function gas exchange Gattinoni hemodynamic hypoxic improved increased induced inflammatory inflation inhaled nitric oxide levels liquid ventilation lung units lung volume macrophages measurements mechanical ventilation membrane mortality neutrophil normal outcome P-V curve patients with acute patients with ARDS PEEP perflubron perfluorocarbon perfusion permeability permissive hypercapnia physiological positive end-expiratory pressure prone position protein pulmonary artery pulmonary edema pulmonary hypertension pulmonary vascular rats receptor recruitment reduced regions Respir Crit respiratory distress syndrome respiratory muscle respiratory system response Rev Respir risk sepsis septic shock severe studies surfactant technique therapy tidal volume tients tion tissue TNF-a ventilatory ventricular weaning