Addiction: From Biology to Drug Policy
Drug addiction is a brain disease--that's the modern view and it is fully expressed in this up-to-date book. Among the many volumes on drugs written for lay readers, this one is unique in the breadth of its coverage and the depth of its science. The first part gives a clear scientificaccount of the nature of addiction, stressing neurobiology and addictive behavior and describing the "highs" that drugs can produce. The second section covers the seven families of addictive drugs, with emphasis on their actions in the brain and on psychological aspects: nicotine, alcohol, heroinand other opiates, cocaine and amphetamines, marijuana, caffeine, and hallucinogens like LSD. The third section deals with laws and drug control policies. Throughout, the author gives many interesting personal accounts of addiction research, to which he has highlighted new research on the geneticsand neurobiology of susceptibility to addiction.
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DRUGS AND THE BRAIN I
The Brains Own Drugs
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abstinence acetylcholine action active addictive drugs alcohol addicts amino acids amphetamines animal antagonist become behavior benzodiazepines binding blood brain caffeine cannabis cause cell chapter chemical cigarette clinic cocaine coffee craving crime criminal dicts disease disulfiram dopamine dosage dose drink Drug Abuse drug addiction drug policy endogenous opioids especially experiments GABA gene genetic hallucinogens harm harm reduction heroin heroin addicts human illicit drugs increase injection intravenous drug users law enforcement levels ligand long-term lung marijuana membranes ment methadone maintenance morphine naloxone naltrexone National needle exchanges nerve neurons neurotransmitter nicotine addiction nicotinic acetylcholine receptors ONDCP opiate opioid receptors pain patients peptide percent placebo produce prohibition protein psychoactive drugs public health reduce regulation relapse release reward pathway self-administration smoking social society stimulation studies substance syringes tion tobacco toxic traffickers treatment typically urine withdrawal syndrome