Adenosine in the Nervous System
This volume in a series on neuroscience provides an overview of the
last 20 years of research into the biochemistry, physiology,pharmacology and clinical therapeutic potential of adenosine and its analogues in the nervous system. Among the topics covered are adenosine transport in nervous systemtissues, adenosine production and metabolism and the electropharmacology of adenosine.
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Chapter 2 Adenosine production and metabolism
Chapter 3 ATP receptors and their physiological roles
classification and distribution
Chapter 5 The adenosine receptor molecule
Chapter 6 Postreceptor mechanisms
Chapter 8 Release of a denosine and ATP from nervous tissue
Chapter 9 Electropharmacology of adenosine
Chapter 10 Potential therapeutic roles for adenosine in neurologic disease
Chapter 11 Adenosine and the central nervous system control of autonomic function
A-kinase A2 receptors acetylcholine actions of adenosine activity adenosine analogues adenosine antagonists adenosine receptor adenosine transport adenosinergic adenylate cyclase adenylyl afﬁnity agonists binding sites Biochem Biol Brain Res Bruns Burnstock calcium carotid body cells Chem chemoreceptors cholinergic compound concentrations cortex CREB cyclic AMP Daly deaminase Deckert decrease deﬁciency deﬁne Dunwiddie effects of adenosine el al endogenous enzyme excitatory extracellular ﬁndings ﬁrst Fredholm function G proteins ganglia Geiger guinea-pig hippocampus hypoxia increase inhibition inhibitors interactions involved Jarvis kinase Lett ligands Marangos mediated Meghji membrane metabolism muscle NECA nervous system Neurochem neurones Neurosci neurotransmitter Newby NMDA noradrenaline nucleoside nucleoside transport P2 purinoceptors peripheral Pharmacol Pharmacology Phillis phosphorylation Physiol physiological postsynaptic potential presynaptic purine purinergic R-PIA radioligand Reddington region respiration responses Ribeiro second messenger selective signiﬁcance slices speciﬁc stimulation Stone striatum studies subunits suggested sympathetic nerves synaptosomes theophylline tissues transmitter uptake vascular xanthine