Adipose Tissue Development: From Animal Models to Clinical Conditions

Front Cover
Claire Levy-Marchal, Luc Pénicaud
Karger Medical and Scientific Publishers, 2010 - Medical - 96 pages
2 Reviews
Nowadays, adipose tissue is not only regarded as an organ of storage related to fuel metabolism but also as an endocrine organ involved in the regulation of insulin sensitivity, lipids and energy metabolism.These proceedings cover the nervous regulation of both white and brown adipose tissue mass. Different physiological parameters such as metabolism (lipolysis and thermogenesis) and secretory activity (leptin and other adipokines) are reviewed. The plasticity of adipose tissue (proliferation, differentiation and apoptosis) showing the presence of a neural feedback loop between adipose tissue and the brain, which plays a major role in the regulation of energy homeostasis, is discussed.Merging basic knowledge and various clinical conditions, this thorough review is of great interest to both scientists and physicians, in particular pediatricians, interested in obesity, endocrinology and nutrition.
 

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Contents

Genetic and Acquired Diseases of Adipose Tissue
1
The Emergence of Adipocytes
21
Biological Aspects
31
A Role for CancerAssociated Adipocytes?
45
Early Determinants of Obesity
53
Metabolic Syndrome in Childhood Causes and Effects
62
A Role for Adipose Tissue?
73
The Neural Feedback Loop between the Brain and Adipose Tissues
84
Author Index
93
Subject Index
94
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